Hydrocodone 10/325mg

Hydrocodone 10mg / 325mg is a prescription opioid combination medicine used to relieve moderate to severe pain. It combines Hydrocodone with acetaminophen for effective pain management under medical supervision.

Brand: Hydrocodone
Strength: 10mg / 325mg
Generic: Hydrocodone / Acetaminophen
Use-case: Moderate to severe pain, post-surgery pain, musculoskeletal injuries

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Hydrocodone 10mg / 325mg is a prescription-strength opioid analgesic used to manage moderate to severe pain that cannot be controlled with non-opioid medications. The combination of hydrocodone (an opioid) and acetaminophen (a pain reliever/fever reducer) provides dual-action pain relief, making it effective for post-operative, injury-related, or chronic pain.

Hydrocodone works by binding to opioid receptors in the brain and spinal cord, blocking pain signals and altering the perception of pain. Acetaminophen enhances pain relief and helps reduce discomfort efficiently.

Because of the risk of dependence and sedation, this medicine must be used strictly according to doctor’s instructions. It is typically prescribed for short-term use, although chronic pain cases may require careful long-term monitoring.

  • Dosage is individualized, based on severity of pain, prior opioid use, and patient tolerance.

  • Typical adult dose: 1 tablet every 4–6 hours as needed for pain, not exceeding 6 tablets per day (or as prescribed).

  • Extended-release or high-strength tablets should never be crushed, chewed, or broken, as this can release too much medicine at once.

  • Overuse may lead to respiratory depression, dependence, or overdose.

  • Short-term usage is preferred, and long-term use should be closely monitored by a healthcare professional.

Tip: Take with food or milk if stomach upset occurs, and maintain consistent timing to optimize effectiveness.

  • Swallow tablets whole with a full glass of water; do not crush or chew.

  • Can be taken with or without food, but food may reduce stomach discomfort.

  • Avoid alcohol, sedatives, or other opioids while taking this medicine.

  • Monitor for drowsiness, dizziness, or unusual behavior, and report persistent symptoms to your doctor.

  • Keep track of your doses to prevent accidental overdose.

  • Do not abruptly stop long-term therapy; tapering may be required to prevent withdrawal symptoms.

Hydrocodone 10mg / 325mg is designed to provide effective relief from moderate to severe pain, improve mobility, and enhance patient comfort safely.

  • Prescription required; never self-medicate.

  • Avoid use in patients with respiratory depression, severe asthma, liver disease, or history of substance abuse.

  • May cause drowsiness, constipation, nausea, or impaired coordination; avoid driving or operating machinery until effects are known.

  • Elderly patients may require lower doses due to increased sensitivity.

  • Pregnant or breastfeeding women must consult a healthcare professional before use.

  • Long-term or excessive use can result in dependence, tolerance, or overdose.

  • Inform your doctor about all medications being taken to prevent harmful interactions.

Common Side Effects:

  • Drowsiness or fatigue

  • Nausea and vomiting

  • Constipation

  • Dizziness or lightheadedness

  • Dry mouth

  • Mild headache

Serious Side Effects (Seek Immediate Help):

  • Severe allergic reactions (rash, swelling, difficulty breathing)

  • Respiratory depression (slow or shallow breathing)

  • Extreme drowsiness or confusion

  • Dependence or withdrawal symptoms after prolonged use

  • Severe hypotension or chest pain

Contact your healthcare provider immediately if any serious side effects occur.

  • Store at room temperature (20–25°C), away from light, heat, and moisture.

  • Keep out of reach of children and pets.

  • Dispose of unused or expired tablets according to local pharmacy or municipal guidelines.

  • Do not share prescription medication with others.

Proper storage ensures the safety, effectiveness, and stability of the medicine.